Genomic Engineering Services

Our Genomic Engineering Service offers a streamlined process for turning your animal model idea into reality. Simply share your project concept and the gene of interest, and we'll handle the rest.

The journey begins with a brief personalized technical meeting where we delve into the specifics of your project. Our team of experts will then craft a comprehensive project strategy, outlining all technical aspects - from project initiation to the delivery of the final animal model.

We'll navigate you through the intricacies of employing CRISPR/Cas9 or Integrase directly in embryos versus ES-cells, elucidating the advantages and disadvantages for achieving constitutive or conditional knockouts or knock-ins.

Throughout the project, expect regular updates on the status, accompanied by documentation of publishing quality. Here are the estimated timelines:

• A standard gene knock-out project typically spans 4-6 months.
• More intricate gene targeting knock-ins or conditional knockouts as well as Rosa26 large knock-ins may extend to 6-9 months.
• Opting for the traditional approach of targeting embryonic stem cells and subsequent blastocyst injection for chimeric formation typically takes 10-12 months.